Monoclonal Antibody Therapy

Cheyenne Regional Medical Group Now Providing Monoclonal Antibody Therapy
Cheyenne Regional Medical Group is now providing monoclonal antibody therapy for COVID-19 positive outpatients on Mondays, Wednesdays and Fridays. Treatment is by provider referral and appointment only. Once a primary care provider refers a patient for treatment, CRMG will call the patient to schedule an appointment. Patients will need to stay at the clinic for approximately 2.5 hours for treatment and post-treatment observation.

Who is NOT eligible for monoclonal antibody therapy?

  • Those who are hospitalized due to COVID-19
  • Those who require oxygen therapy due to COVID-19
  • Those who are on chronic oxygen therapy due to an underlying condition (not related to COVID-19) and who require an increase in baseline oxygen flow rate because of COVID-19

Who is eligible for monoclonal antibody therapy?

Monoclonal antibody therapy is available to individuals who meet the following criteria:

  • Have a positive COVID-19 test AND have not been admitted to the hospital AND
  • Have a high risk** for developing severe COVID-19 AND
  • Are 12 years of age or older (and are at least 88 pounds)

Who is eligible for preventive monoclonal antibody therapy?

Preventive monoclonal antibody therapy is available to individuals who have been exposed to COVID-19 (consistent with the CDC’s close contact criteria*) and who meet the following criteria:

  • Are at high risk** for developing severe COVID-19 AND
  • Are 12 years of age or older (and are at least 88 pounds) AND
  • Are not fully vaccinated or are vaccinated but are immunocompromised

*In some cases, direct exposure isn’t a criterion for getting monoclonal antibody therapy.

If you meet the criteria above and are at high risk of exposure to an individual infected with COVID-19 in the same institutional setting (for example, a nursing home or prison), you are eligible for post-exposure preventive monoclonal antibodies.

**High risk includes any of the following:

  • 65 years of age or older
  • Overweight (body mass index over 25)
  • Pregnancy
  • Chronic kidney disease
  • Diabetes (Type 1 and Type 2)
  • Weakened immune system
  • Currently receiving immunosuppressive treatment
  • Cardiovascular disease/hypertension
  • Chronic lung disease
  • Sickle cell disease
  • Neurodevelopmental disorders
  • Medical-related technological dependence

REMINDER: Treatment is by provider referral and appointment only. Once a primary care provider refers a patient for treatment, CRMG will call the patient to schedule an appointment.


Monoclonal Antibody Therapy is not a substitute for vaccination.